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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee80f87eb17a864a94d28f91596e963d77ee92ce8417047452088e105a0f6f7' 
  AND token = 'efAS2GYR8BTxN4E1WivuiMHfyPNad8DFF5shb+Wjh/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}