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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ee86210f18422ecbf03f9e54e89643c41d7a30193677a350ab53d641311344' 
  AND token = 'nCYcmuFncZfbuhGc76o8Rr0hT+xCMqHQW3VlQbiYWps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}