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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e13170078dd2be10678cc3725af520ac5cc5d050f6318a13da9fcfb2bbb09a' 
  AND token = 'rWdj5B+wVvxYtvsKKiC5rVWtLyy21AM93hVS01iz8rA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}