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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df3f83accd7d6f84654135b852fb514fd01d190a5314d436207513de1c1004c' 
  AND token = 'ItieWvZuQZPg5y4Sg5uP3UjD9uGmjYCdzW41agu21Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}