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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff500add589f1a7b2424da977e750cfd76fb67110c10164d397fd4f7da724078' 
  AND token = 'bL1Ft9z+xIm+NGhERL81vK8onTLXenmSGOqEbIrgg+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}