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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d63812bf073d0944d85f95718e9ac0d9cd961b11869c698a95669b613f848d' 
  AND token = '7sk7w8k5/xYJi0SVuuOS42yGTMIyY+nZIELGRjlIDXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}