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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd34d82bd6b37a33e158a4fcfc79df4f724d46c0441466da1a06185fa284b4d' 
  AND token = 'eTyJHtPfAdYH3/jl+aYjDfouDMw6L8dF18bfITNb77I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}