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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163dfb9391b569a8e15c1a6a2e624a146398cb6bebd33108331954c0a299f919' 
  AND token = 'Wcm49/bmgMloEKfZ2alRMmhYrkb8nP/3tD84B+ASdnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}