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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef349e313e2dc871c9bd9593d23a12f94f74661eb496797bf9e01deedc03cfd4' 
  AND token = '33yMH4EzP+9H12vpB+i46kL7JgtoYFd0/1tWHrX4VdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}