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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08d48afad393d8d400c180ae50d98d7d8b3c4dd56e7914b3b087354746fc567' 
  AND token = 'VmCeFZ42jzbCEs1RC69POYFDW9znSZ/xUf4gK6zRbxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}