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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c7a7c80f15a05151587d7bbcb7e9947e2e7fab8bc27ddc6c29d8b951f8d404' 
  AND token = 'TnMws08VBKtQFx1ubl/9rTAGrC8uvroeAw3MyZmrBZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}