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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa8f06f931f799534e1e36a3a761cbf75828e7df0b60495390d70da502003584' 
  AND token = 'xCAKEjSc2SmW1wDn1PRBps3WpSMBMywNz3yKMjzgW2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}