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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5ddf20e2de2268b4a7542b6f4d92d93be678f061971c8d07f517de17c87384' 
  AND token = 'aLm3pztEE5INDPr8Leb/H7GMb7jiDuPGsTS+GWzKMJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}