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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '577c3e1f000ce6c55b11c5d01753531f88b6c9d2e30c773d2caf2abeccf79630' 
  AND token = 'VrXVeoKR30Hptpgis76m1APfNxYPRWxuHGAifGUxAO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}