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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea89a195f2d9865e66aa92ff6b1f595bcdb516caec66ddd7d006fb4eef018e69' 
  AND token = '2WH/nYEjagqJ1BHF5V0bo2MI2AFwKkcZa1At3EZKGIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}