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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a7a980beb33956be20156c4873f7d86fe24c03b84241a095a4fc63027ee222' 
  AND token = 'dX/KLb27WpLKULSWlfCO24XsNHQl679wyIR5SuH2R/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}