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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8b23b8dd05834505fc17cea6de4fc5fcf00612c30066078bb9d221e8fa0606' 
  AND token = 'z2gb5b9z4QsN5FaGDVx5NSjlUjvitWqRP5HIKmqbX1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}