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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6bdc6e64428c5f2e81f7045677e898a330d55fb82e947b43eca08f8c24f043' 
  AND token = 't1AY4gl1l7t9+7Yom1DTo+xIcta/Bnvvvcvsg5iZNeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}