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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d37bf3ed99e53eaab65b731350d4a8a4986758cfa3f905eb8ef1bee52e4565' 
  AND token = 'Kg+9jtp99DWdXSg9g/tAMmp2S4ALcSIigYMUo7XcqwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}