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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6833608436dad8961879671699c14ff17538b60e479e9aab9b79a8650b3e0b4' 
  AND token = 'MhpV6PeGPrgEM3+d2R1X8pL/QTskcXmaGCRbCsVcuFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}