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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cfe74caff531943bbc02ddd164b2a635e0592ba73f2d96161d195b00a05378a' 
  AND token = 'fM9eRCaTPgCSCFgqrdwNd7e6EEjKJ1SQtDbnRflMO8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}