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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dd3606a09d65094d4f9633014bb55fe018e6875bea5caada3ef02f7dc5fd0e7' 
  AND token = 'q+ID9CDqIUiZvQ9VQZDIIoRvwzMHSdQMAzbw0yqQsXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}