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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373370492824b9f5064b2233676852e8118e1c925212ab2cd857332797c63603' 
  AND token = 'HeTN3D0YopZrI/J0dhYQSfomj67OxbNKH9BtRx7MwcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}