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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f57f9a4ed99302bb17b83b0093e2e39fba252f8709d3fedf3dde95f91b8a2f1b' 
  AND token = 'w6BI3Of1VX9kQDXzXxj7UYgLe7aYTHNk4RpaEhY2qFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}