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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f664a82b35f8b60d9e098523dfd093e064e51f46d1dd1e741534c1cee9bb33' 
  AND token = 'hJB8J6VulxwH0nPVqyI1NX9WNVPIPvJlJ71uxdzrhG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}