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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d12e3ab86264ae2c72fcfd9c624653bf5a68aa000b045d73d5de44515f7610' 
  AND token = 'QDiH63BxRYOW2lUMG6tFeEQlKva8CvaYML41e626V8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}