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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5cbc7696523a32368e81439616bae5b617845f9df9e2ce55f83e262c36ddde8' 
  AND token = 'QZq+FvOcYXlPs/oIaMv//+UISsvv2A+61Pxg6CXvZOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}