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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5cd3869ae7fe10bd3878926b165aff6ee8bdf699abc3ad4097ba1afd9734ec2' 
  AND token = 'D977Q7p7PxrNBq3RY5B0IgoRo1UOZ6uJnIpOGSSFaBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}