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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '071c62efb60b5bb630a614205374784c9023f334e449efcefdc7e3374802b2a7' 
  AND token = 'OGBHvlm4k2lmsvbr0c/wmAnttOG9g0izbqg5NypcJB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}