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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661a6c1211978b12c508da5af2af36a4093b2dd0da3078dd5f17f3789ff974cf' 
  AND token = '1b11Ok6sw2X9SKNYmYv8PsM+mYQNgqxzCuau/vKvIac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}