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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405f1e21fc4400f76422a23a584f22e681afae7fc0c0553c470af864b0e20bfe' 
  AND token = 'VrQ8hF3JcwEWsQ903XOlT34OUwind86dfLX9b9EF5+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}