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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec3169882eab36d0a098efccb3c065ea56dcf8e4f6c74e48d0a9c2ccba594eb' 
  AND token = 'uiZwQ8+0nJbUn/+nAWnb+8kGacNE4TKmQT0EUYAtNUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}