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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f87040de472d93a8e5dc804e0ffe1bdf40adf7af4120685c0978e7b0de220ea' 
  AND token = '4a6aGnLKeb4oBEn751+NChiAr5LvCLGoMjjDMjcKiAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}