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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb3bb34085ba115b3cab9071b151ec8ff9a2caa1535c460b5241bc4951c30ba' 
  AND token = 'uPvAa/PVEWuUOA+G0dQGRo4b08gQ4CKkucn+0lznDqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}