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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28303025f6cc883aa17a6e3743d0be78e0ecfd05eda1937af32571196b9f3b1f' 
  AND token = 'mUq+UGFPW4K5dvZBfOHyZ55G6D3IlYb/rL14+2P5sf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}