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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc7a60612a01a24b604fbe4eadab9cf21e241f780423989e9d4f82956c4bf6d' 
  AND token = 'JkEkmT0VwGXdqb8ykXBrpVRIfqMTWQe16ipRsS7q3qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}