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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ff77cc8abba88a53cab6a14a076334192489b931d27c96d53194cc65ca403c' 
  AND token = 'QY0jrx9v5q4aNgXUDF9pJz4gS5FxYZhp2QIEP9qINF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}