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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f293c618ec872f1a76c8beb0d67361712f800dcbfef5e0de5e4947e50fe6df82' 
  AND token = 'ma7mOSeu0+FbX0dzFIxghyNHswMZwTyWNiTSyZ3iSBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}