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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be88172f4f481d1c3c29bb52111c2a89045265c99a5fd1dcf683ee8f231fd779' 
  AND token = 'XNgrIdlp+vuUwD3LLdt3SqOSH6ML6IWNj2+jfdcUHTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}