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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b22491ca763381d33898dde1b58c8ab78ee11d27a0c3955d035db85d033bb20' 
  AND token = 'GT6CSbTzZh90OeKMIseBwsbnQZRZlMCFVM/vqTzwnQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}