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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a0991c88fce268d1ea2479055e4ae24db6344d66e9079df73c374ebb17a8301' 
  AND token = 'ik7xyyhFr+QHisF+8R3GhE4n/eDvVxCwvhN1AvMcaVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}