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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dadead75c1f410e2ea3bec1530055ae5da864970d1cab0386ded807a067b81' 
  AND token = '/Q2QG+KdortjLCRJAw9Z9E/neHKfUcD7QJQWFZ9Oxvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}