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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759f176d8e50d7ba286eb1d0ad2c737062430eca2ac00c508d0c39be08705ed5' 
  AND token = 'znI4leXSgeTB+zu85WfaTgjxCidZRtR8/GHVAaC0LiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}