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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2aeb0b64a3fd1a3bd98925857c8268c4bfd01e1e1a972ff375f81bec366d626' 
  AND token = 'ceE4qPE7p6aeDJWU4go5TPQS07gO8gIakXuL07qM0QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}