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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5372a5dad3451ee65f94fda122027b08e8ad5ffffa2ed365193a3120664df595' 
  AND token = 'E2ZFNFXs6mdSbCrCHEn5nNd4jHhTJBdJJNpQrvni6SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}