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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a881941a8e9a251416b2487522e8b9fb87b7ee5fd79c5e1bcc52c087acfbe2' 
  AND token = 'XzRKnDIzbrIuzSVkwZMVCSdB6me0ENlmNbHzyevfZUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}