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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e10b7a87afcc019200f7bc671c98ec6262fb573f8d08bee637e9a4b82b02c16' 
  AND token = 'dX3UG/M/7NbdN8mN0gF1hopfvEbcXZMC36cCKm0a97s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}