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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '784b2ff6bfb09ab0eed3b8a147a3a2ca3e060b8144dbace635b29a056e1bca61' 
  AND token = 'Y31JiVzK6qkzmKRVaoWrz01yzS0iTrgY3/VpLEWQ+qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}