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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0a1584a131afd004ccd9d4e73e6b49953c4036e868b37292bbe7524ec164ba' 
  AND token = '5Hxg2xaRpTlurC9pprxbHpjWt9uonzzQOSlWm5ByYMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}