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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '603c86dfb7da100cc78fff710cf4d42fe50e5c22bdbcc8a022880713d3ee657c' 
  AND token = 'e+CxLhWbcTVoLkeW+2zPneFANXE1fUyJAoN4jArPw5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}